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Rabbit anti-NDUFS2 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.7 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:CI 49, CI 49kD, CI-49kD, Complex 1, mitochondrial respiratory chain, 49 KD subunit, Complex I 49kD, Complex I 49kDa subunit, Complex I-49kD, mitochondrial, NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa, NADH dehydrogenase (ubiquinone) Fe S protein 2, 49kDa (NADH coenzyme Q reductase), NADH dehydrogenase [ubiquinone] iron sulfur protein 2, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, NADH ubiquinone oxidoreductase 49 kDa subunit, NADH ubiquinone oxidoreductase NDUFS2 subunit, NADH-ubiquinone oxidoreductase 49 kDa subunit, NADH:ubiquinone oxidoreductase core subunit S2, Ndufs2, NDUS2
UniProt ID:O75306

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:200-1:1000, IHC 1:50-1:200

Immunogen

Synthetic peptide of human NDUFS2

Purification/Format

Affinity purification

Background

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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