Anti-Relish Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Label: | Unconjugated |
Applications
ELISA, Western Blot
Immunogen
This antibody was produced from a rabbit immunized with the KLH-conjugated peptide derived from Drosophila Relish. The IgG fraction of immunized serum was purified by affinity chromatography.
Background
The NF-kB-like transcription factor Relish plays a central role in the innate immune response of Drosophila. Relish is a bipartite NF-kB precursor protein, with an N-terminal Rel homology domain and a C-terminal IkappaB-like domain, similar to mammalian p1 and p15. Unlike mammalian NF-kB proteins, Relish is activated by endoproteolytic cleavage to generate a DNA-binding Rel homology domain (545 a.a.) and a stable IkB-like fragment (426 a.a.).
Product Citations
- (2019) Chen K., Luan X., Liu Q., et al. Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance. Cell Host Microbe . 2019 Apr 10,25(4):537-552.e8. doi: 10.1016/j.chom.2019.02.003.
- (2019) Maitra, U., Scaglione, M.N., Chtarbanova, S. et al. Innate immune responses to paraquat exposure in a Drosophila model of Parkinsons disease. Sci Rep 9, 12714 (2019).
Price
387,00 €
