GBA Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 1mg/mL |
| Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Additional Information | |
|---|---|
| Synonyms: | GBA, GBA1, GCB, GLUC |
| UniProt ID: | P04062 |
Applications
WB
Recommended Dilution
WB 1:500-1:2000
Immunogen
Recombinant fusion protein of human Glucosylceramidase beta
Purification/Format
Affinity purification
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Price
601,00 €
