Recombinant PKR Monoclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | R04-3F2 |
| Host: | Rabbit |
| Reactivity: | Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 300 μg/mL |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
Applications
WB
Recommended Dilution
WB 1:500-1:1000
Immunogen
Recombinant protein of mouse PKR
Purification/Format
Affinity Purified
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Price
365,00 €
