CD156c Polyclonal Antibody
Specifications | |
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Type: | Primary Antibody |
Clonality: | Polyclonal |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Isotype: | IgG |
Label: | Unconjugated |
Concentration: | 210 μg/mL |
Buffer: | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Additional Information | |
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Synonyms: | A disintegrin and metalloprotease domain 10, A disintegrin and metalloproteinase domain 10, AD 10, AD10, AD18, ADA10, ADAM 10, ADAM metallopeptidase domain 10, ADAM10, CD 156c, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain containing protein 10, Disintegrin and metalloproteinase domain-containing protein 10, HsT 18717, HsT18717, Kuz, Kuzbanian, Kuzbanian protein homolog, Kuzbanian, Drosophila, homolog of, MADM, Mammalian disintegrin metalloprotease, Mammalian disintegrin-metalloprotease, RAK |
UniProt ID: | O14672, O35598, Q10743 |
Applications
WB
Recommended Dilution
WB 1:500-1:1000
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ADAM10
Purification/Format
Affinity purification
Background
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).
Price
496,00 €