GFRA1 Polyclonal Antibody
Specifications | |
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Type: | Primary Antibody |
Clonality: | Polyclonal |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Isotype: | IgG |
Label: | Unconjugated |
Concentration: | 1.92 mg/mL |
Buffer: | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Additional Information | |
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Synonyms: | GDNF family receptor alpha 1, GDNF family receptor alpha-1, GDNF R, GDNF RA, GDNF receptor alpha, GDNF receptor alpha-1, GDNFR alpha 1, GDNFR alpha, GDNFR, GDNFR-alpha-1, GDNFRA, GDNFRalpha, GFR alpha 1, GFR alpha1, GFR-alpha-1, GFRA 1, Gfra1, GFRA1, GFRalpha1, Glial cell line derived neurotrophic factor receptor alpha, GPI linked anchor protein, MGC23045, PI linked cell surface accessory protein, RET 1L, RET ligand 1, RET1L, RETL 1, RETL1, TGF beta related neurotrophic factor receptor 1, TGF-beta-related neurotrophic factor receptor 1, TRNR 1, TRNR1 |
Accn. No.: | NP005255 |
UniProt ID: | P56159 |
Applications
WB, IHC
Recommended Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen
Synthetic peptide of human GFRA1
Purification/Format
Antigen affinity purification
Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
- Catalog Number
E-AB-53255-20ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
202,00 €