GFRA1 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1.92 mg/mL
Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Additional Information
Synonyms:GDNF family receptor alpha 1, GDNF family receptor alpha-1, GDNF R, GDNF RA, GDNF receptor alpha, GDNF receptor alpha-1, GDNFR alpha 1, GDNFR alpha, GDNFR, GDNFR-alpha-1, GDNFRA, GDNFRalpha, GFR alpha 1, GFR alpha1, GFR-alpha-1, GFRA 1, Gfra1, GFRA1, GFRalpha1, Glial cell line derived neurotrophic factor receptor alpha, GPI linked anchor protein, MGC23045, PI linked cell surface accessory protein, RET 1L, RET ligand 1, RET1L, RETL 1, RETL1, TGF beta related neurotrophic factor receptor 1, TGF-beta-related neurotrophic factor receptor 1, TRNR 1, TRNR1
Accn. No.:NP005255
UniProt ID:P56159

Applications

WB, IHC

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Synthetic peptide of human GFRA1

Purification/Format

Antigen affinity purification

Background

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Price
202,00 €
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