α-SMA Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:a actin, AAT6, ACTA, ACTA2, Actin alpha 2 smooth muscle aorta, Actin aortic smooth muscle, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha 2 actin, Alpha actin 2, Alpha cardiac actin, alpha sma, Alpha-actin-2, Cell growth inhibiting gene 46 protein, Cell growth-inhibiting gene 46 protein, GIG46, Growth inhibiting gene 46, MYMY5, ACTC, ACTC, ACTC1, Actin alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ASD5, CMD1R, CMH11, LVNC4, a actin, Actin alpha skeletal muscle, Actin, actin, alpha 1, skeletal muscle 1, actin, alpha 1, skeletal muscle, Actin, alpha skeletal muscle, actina, actine, ACTS, aktin, Alpha Actin 1, , ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, nemaline myopathy type 3
UniProt ID:P62736, P68133, P63267

Applications

WB, IHC-p, IF

Recommended Dilution

WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200

Immunogen

Synthesized peptide derived from α-SMA

Purification/Format

Affinity purification

Background

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.

Product Citations

Price
202,00 €
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