α-SMA Polyclonal Antibody
Specifications | |
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Type: | Primary Antibody |
Clonality: | Polyclonal |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Isotype: | IgG |
Label: | Unconjugated |
Concentration: | 1 mg/mL |
Buffer: | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
Additional Information | |
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Synonyms: | a actin, AAT6, ACTA, ACTA2, Actin alpha 2 smooth muscle aorta, Actin aortic smooth muscle, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha 2 actin, Alpha actin 2, Alpha cardiac actin, alpha sma, Alpha-actin-2, Cell growth inhibiting gene 46 protein, Cell growth-inhibiting gene 46 protein, GIG46, Growth inhibiting gene 46, MYMY5, ACTC, ACTC, ACTC1, Actin alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ASD5, CMD1R, CMH11, LVNC4, a actin, Actin alpha skeletal muscle, Actin, actin, alpha 1, skeletal muscle 1, actin, alpha 1, skeletal muscle, Actin, alpha skeletal muscle, actina, actine, ACTS, aktin, Alpha Actin 1, , ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, nemaline myopathy type 3 |
UniProt ID: | P62736, P68133, P63267 |
Applications
WB, IHC-p, IF
Recommended Dilution
WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200
Immunogen
Synthesized peptide derived from α-SMA
Purification/Format
Affinity purification
Background
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.
Product Citations
- Azam Salari, Kunyan Zhou, Katerina Nikolovska, Ursula Seidler, Mahdi Amiri (2023) Human Colonoid–Myofibroblast Coculture for Study of Apical Na+/H+ Exchangers of the Lower Cryptal Neck Region INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cai Zhang, Qi Shao, Mingchao Liu, Xueying Wang, Juan J. Loor, Qianming Jiang, Shunan Cuan, Xinwei Li, Jianguo Wang, Yuanxiao Li, Lei He, Yong Huang, Guowen Liu, Lin Lei (2023) Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver JOURNAL OF DAIRY SCIENCE
- Manar A. Didamoony, Ahmed M. Atwa, Lamiaa A. Ahmed (2023) Modulatory effect of rupatadine on mesenchymal stem cell-derived exosomes in hepatic fibrosis in rats: A potential role for miR-200a LIFE SCIENCES
- Noha H. Habashy, Shaimaa A. Olleak, Marwa M. Abu-Serie, Nadia Z. Shaban (2023) A new approach for the treatment of bleomycin-induced rat pulmonary injury by combined protein fraction of major royal jelly protein 2 and its isoform X1 BIOMEDICINE & PHARMACOTHERAPY
- Sukanya V. S., Pravin Shankar Giri, Vijaykumar Nellore, Subha Narayan Rath (2023) Osteomatrix as a personalized 3D tissue-specific invasion test-bed for oral carcinoma Biomaterials Science
- Catalog Number
E-AB-34268-20ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
202,00 €