ATG4A Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human
Isotype:IgG
Label:Unconjugated
Concentration:0.3 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:AI627006, APG4 autophagy 4 homolog A, Apg4a, ATG4 autophagy related 4 homolog A (S. cerevisiae), ATG4 autophagy related 4 homolog A, ATG4A, ATG4A, Atg4al, AUT like 2 cysteine endopeptidase, AUT-like 2 cysteine endopeptidase, Autl2, Autophagin 2, Autophagin-2, Autophagy related 4A cysteine peptidase, Autophagy related cysteine endopeptidase 2, Autophagy related protein 4 homolog A, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, AV169859, Cysteine protease ATG4A, hAPG4A, MGC107179
Accn. No.:NP_443168
UniProt ID:Q8WYN0

Applications

WB, IHC

Recommended Dilution

WB 1:200-1:1000, IHC 1:25-1:100

Immunogen

Synthetic peptide of human ATG4A

Purification/Format

Affinity purification

Background

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Price
348,00 €
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