THBD Recombinant Monoclonal Antibody [15C7]
Specifications | |
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Type: | Primary Antibody |
Clonality: | Monoclonal |
Clone Name: | 15C7 |
Host: | HEK293F Cell |
Reactivity: | Human |
Isotype: | Rabbit IgG |
Label: | Unconjugated |
Additional Information | |
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Synonyms: | Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141), THBD, THRM |
UniProt ID: | P07204 |
Applications
ELISA, IHC
Recommended Dilution
Recommended dilution: IHC:1:50-1:200
Immunogen
A synthesized peptide derived from human THBD
Purification/Format
Affinity Chromatography
Background
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Price
459,00 €