MADCAM1 Recombinant Monoclonal Antibody [12B5]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 12B5 |
| Host: | HEK293F Cell |
| Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Label: | Unconjugated |
| Additional Information | |
|---|---|
| Synonyms: | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (hMAdCAM-1), MADCAM1 |
| UniProt ID: | Q13477 |
Applications
ELISA, FC
Recommended Dilution
Recommended dilution: FC:1:50-1:200
Immunogen
A synthesized peptide derived from human MADCAM1
Purification/Format
Affinity Chromatography
Background
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Price
459,00 €
