MYLK Recombinant Monoclonal Antibody [28C5]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 28C5 |
| Host: | HEK293F Cell |
| Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Label: | Unconjugated |
| Additional Information | |
|---|---|
| Synonyms: | Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form], MYLK, MLCK MLCK1 MYLK1 |
| UniProt ID: | Q15746 |
Applications
ELISA, WB, FC
Recommended Dilution
Recommended dilution: WB:1:500-1:2000, FC:1:50-1:200
Immunogen
A synthesized peptide derived from human MYLK
Purification/Format
Affinity Chromatography
Background
Calcium/calmodulin-dependent myosin light chain kinase is vital for smooth muscle contraction by phosphorylating myosin light chains (MLC) and regulating actin-myosin interaction. It influences inflammation, cell motility, airway hyperreactivity, and asthma-related activities. Required for airway and gastrointestinal muscle contraction, cell survival, wound healing, and migration. Also involved in various signaling pathways and membrane localization. Critical for fibroblast apoptosis, tight junction regulation, and mediating barrier injuries. Important in cellular responses to infections and cancer proliferation.
Price
459,00 €
