TACC3 Recombinant Monoclonal Antibody [10G7]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 10G7 |
| Host: | HEK293F Cell |
| Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Label: | Unconjugated |
| Additional Information | |
|---|---|
| Synonyms: | Transforming acidic coiled-coil-containing protein 3 (ERIC-1), TACC3, ERIC1 |
| UniProt ID: | Q9Y6A5 |
Applications
ELISA, WB, IHC
Recommended Dilution
Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Immunogen
A synthesized peptide derived from human TACC3
Purification/Format
Affinity Chromatography
Background
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. May be involved in the control of cell growth and differentiation. May contribute to cancer.
Price
459,00 €
