GSK3B Recombinant Monoclonal Antibody [9G11]
Specifications | |
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Type: | Primary Antibody |
Clonality: | Monoclonal |
Clone Name: | 9G11 |
Host: | HEK293F Cell |
Reactivity: | Human |
Isotype: | Rabbit IgG |
Label: | Unconjugated |
Additional Information | |
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Synonyms: | Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1), GSK3B |
UniProt ID: | P49841 |
Applications
ELISA, WB, IHC, IF
Recommended Dilution
Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
Immunogen
A synthesized peptide derived from human GSK3 beta
Purification/Format
Affinity Chromatography
Background
This gene encodes a serine-threonine kinase from the glycogen synthase kinase subfamily. It negatively regulates glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptosis. It's linked to Parkinson's and Alzheimer's diseases due to defects in this gene.
Price
459,00 €