LPAR1 Recombinant Monoclonal Antibody [4C3]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 4C3 |
| Host: | HEK293F Cell |
| Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Label: | Unconjugated |
| Additional Information | |
|---|---|
| Synonyms: | Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2), LPAR1, EDG2 LPA1 |
| UniProt ID: | Q92633 |
Applications
ELISA, WB
Recommended Dilution
Recommended dilution: WB:1:500-1:5000
Immunogen
A synthesized peptide derived from human EDG2
Purification/Format
Affinity Chromatography
Background
Lysophosphatidic acid (LPA) receptor influencing actin cytoskeleton, cell migration, differentiation, proliferation, and responses to damage. Activates G-proteins, triggers Ca(2+) increase, MAP kinase activation, and Rho signaling. Shapes cells, drives neurite retraction and stress fiber formation. Involved in chemotaxis, inflammation, cell proliferation, and brain/neuron development. Crucial for skeleton and dentate gyrus neuron processes. Implicated in pain perception and neuropathic pain initiation.
Price
459,00 €
