NF-kB p65 Polyclonal Antibody
Specifications | |
---|---|
Type: | Primary Antibody |
Clonality: | Polyclonal |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Isotype: | IgG |
Label: | Unconjugated |
Additional Information | |
---|---|
Synonyms: | RELA; NFKB3; p65; transcription factor p65 |
UniProt ID: | Q04206 |
Applications
WB, IF, IP
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NF-kB p65/RelA (NP_068810.3)
Purification/Format
Affinity Purification
Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
- Catalog Number
A71091-100-EP - Supplier
EpigenTek - Size
- Shipping
Blue Ice
Price
605,00 €