SIN3B Polyclonal Antibody, FITC Conjugated
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human |
| Isotype: | IgG |
| Label: | FITC |
| Additional Information | |
|---|---|
| Synonyms: | Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b, SIN3B |
| UniProt ID: | O75182 |
Applications
ELISA
Recommended Dilution
Recommended dilution: ELISA 1:100-1:500
Immunogen
Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
Purification/Format
Protein G purified
Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Price
475,00 €
