Anti-Bax Antibody, Sodium Azide Free
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Host: | Mouse |
| Reactivity: | Human, Non-Human Primates |
| Isotype: | Mouse IgG1 |
| Label: | Unconjugated |
| Concentration: | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
Applications
FC, IF, WB, IHC (Prediluted format)
Immunogen
Recombinant full-length human protein was used as the immunogen for the Bax antibody.
Background
Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
- Catalog Number
188-10656-SAF-RB - Supplier
RayBiotech - Size
- Shipping
Blue Ice
Price
840,00 €
