Anti-Primates NGFR Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Host: | Mouse |
| Reactivity: | Human, Non-Human Primates |
| Isotype: | Mouse IgG1, kappa |
| Label: | Unconjugated |
| Concentration: | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Applications
FC, IF, IHC (Prediluted format)
Immunogen
Recombinant human protein was used as the immunogen for the NGFR antibody.
Background
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Price
512,00 €
