Anti-NKX2.2 Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Host: | Mouse |
| Reactivity: | Human, Mouse, Rat, Chicken |
| Isotype: | Mouse IgG2b, kappa |
| Label: | Unconjugated |
| Concentration: | Prediluted in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
Applications
IHC (Prediluted format)
Immunogen
Human NKX2.2 recombinant protein was used as the immunogen for this antibody.
Background
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
- Catalog Number
188-10146-IHC-RB - Supplier
RayBiotech - Size
- Shipping
Blue Ice
Price
840,00 €
