Histone Octamer, Recombinant Human
Product Description
Human histone octamers (two each of histones H2A, H2B, H3 and H4) are made from recombinant histones expressed in E. coli. Octamers are the protein component of nucleosomes, the basic subunit of chromatin. Assembling this product with DNA bearing a 601 Widom sequence produces a nucleosome (e.g. Cat# 18-0005-EPC, 18-0006-EPC). The 601 Widom sequence, originally discovered by Lowary and Widom [1], has high affinity for octamers.
Product Citations
- Taichi Shiraishi, Yuta Katayama, Masaaki Nishiyama, Hirotaka Shoji, Tsuyoshi Miyakawa, Taisuke Mizoo, Akinobu Matsumoto, Atsushi Hijikata, Tsuyoshi Shirai, Kouta Mayanagi, Keiichi I Nakayama (2024) The complex etiology of autism spectrum disorder due to missense mutations of CHD8. Molecular psychiatry
- John Arne Dahl, Arne Klungland (2023) ChIP-seq assays
- Dian Spakman, Tinka V M Clement, Andreas S Biebricher, Graeme A King, Manika I Singh, Ian D Hickson, Erwin J G Peterman, Gijs J L Wuite (2022) PICH acts as a force-dependent nucleosome remodeler. Nature communications
- Sumanth K Maheshwaram, Divya Shet, Serene R David, Mahesh B Lakshminarayana, Gautam V Soni (2022) Nanopore Sensing of DNA-Histone Complexes on Nucleosome Arrays. ACS sensors
- Aliaksandra Radzisheuskaya, Pavel V. Shliaha, Vasily V. Grinev, Daria Shlyueva, Helene Damhofer, Richard Koche, Vladimir Gorshkov, Sergey Kovalchuk, Yingqian Zhan, Keli L. Rodriguez, Andrea L. Johnstone, Michael-C Keogh, Ronald C. Hendrickson, Ole N. Jensen, Kristian Helin (2021) Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcriptional regulation and cellular homeostasis Molecular cell
- Catalog Number
16-0001-EPC - Supplier
EpiCypher - Size
- Shipping
Dry Ice
Price
297,00 €
