Recombinant Mouse MIF Protein (His Tag)
| Specifications | |
|---|---|
| Molecular Weight: | 13.5 kDa |
| Tag: | C-6His |
| Source: | E.coli |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg as determined by the LAL method. |
| Format: | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Additional Information | |
|---|---|
| Synonyms: | Macrophage migration inhibitory factor; Delayed early response protein 6; DER6; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase; |
| Organism: | Mouse |
| Accn. No.: | P34884 |
Sequence Information
Pro2-Ala115
Background
Macrophage migration inhibitory factor(MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.
Price
233,00 €
