Recombinant Human Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA), partial (Active)
Specifications | |
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Molecular Weight: | 41.8kDa |
Tag: | C-Terminal 6Xhis-Myc-Tagged |
Source: | Mammalian Cells |
Purity: | >95% by SDS-PAGE |
Endotoxin Level: | <1.0 EU/ug, by LAL method |
Activity Assay: | ①Measured by its binding ability in a functional ELISA. Immobilized SIRPA at 2 μg/ml can bind human CD47, the EC50 of human SIRPA protein is 58.30-85.04 ng/ml. ②Human SIRPA protein His/Myc tag captured on COOH chip can bind Human CD47 protein Fc tag with an affinity constant of 19.1 nM as detected by LSPR Assay. |
Format: | Lyophilized powder |
Additional Information | |
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Synonyms: | Brain Ig-like molecule with tyrosine-based activation motifs (Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD_antigen: CD172a; SHP substrate 1; SHPS-1; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP) |
Organism: | Human (Homo sapiens) |
Accn. No.: | P78324 |
Sequence Information
Partial 31~370aa
Price
527,00 €