Rat Vascular Endothelial Growth Factor-165 (VEGF-165)

Specifications
Molecular Weight:19.4/38.7
Tag:None
Source:E.coli
Purity:≥95%
Activity:8 ng/mL
Activity Assay:HUVEC proliferation
Format:Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5
Additional Information
Synonyms:VEGF-A, VPF, glioma-derived endothelial cell mitogen
Organism:Rat
Accn. No.:P16612-2

Sequence Information

MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPENHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

Background

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
Price
623,00 €
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