Rat Interleukin-1 beta (IL-1 beta)
| Specifications | |
|---|---|
| Molecular Weight: | 17,4 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | Currently undetermined |
| Activity Assay: | Bioactive protein, but not acceptance criteria established |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | Catabolin, LAF, EP, LEM, MCF |
| Organism: | Rat |
| Accn. No.: | Q63264 |
Sequence Information
MVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS
Background
Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1β and the independently regulated IL-1α protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
- Catalog Number
300-30-500UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
4.251,00 €
