Rat Interferon gamma (IFN gamma)

Specifications
Molecular Weight:15.6 / 31.2
Tag:None
Source:E.coli
Purity:≥95%
Activity:NA
Activity Assay:Bioactive protein, but not acceptance criteria established
Format:Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, 100 mM Sodium Chloride, pH 7.5
Additional Information
Synonyms:Type II interferon, T cell interferon, Immune Interferon, MAF
Organism:Rat
Accn. No.:P01581

Sequence Information

MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC

Background

Interferon gamma (IFNγ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFNγ is produced by T cells and natural killer cells following antigen-specific activation. IFNγ binds IFNγ receptors (IFNγR1 and IFNγR2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFNγ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules.
Price
1.486,00 €
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