Porcine Interleukin-4 (IL-4)

Specifications
Molecular Weight:12,7
Tag:None
Source:E.coli
Purity:≥95%
Activity:2 ng/mL
Activity Assay:TF-1 cell proliferation
Format:Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5
Additional Information
Synonyms:B-cell stimulatory factor-1, BSF-1, BCDF, BCGF
Organism:Porcine
Accn. No.:Q04745

Sequence Information

MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC

Background

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.
Price
969,00 €
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