Immortalized Mouse alpha-GalA-/o Schwann Cells (1089C1)

Specifications
Cell Category:Immortalized Cell Lines
Organism:Mouse
Tissue of Origin:Brain
Morphology:Spindle-shaped
Culture Properties:Adherent
Immortalization Method:Spontaneous immortalization
Marker:S100, laminin, p75NTR, GFAP, globotriaosylceramide (Gb3)

Propagation

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Additional Information

Immortalized Mouse alpha-GalA-/o Schwann Cells (1089C1) is a spontaneously immortalized cell line from Fabry mice. 1089C1 has a disrupted Gla gene allele and exhibits a distinct Schwann cell morphology and biochemical phenotype (α-Galactosidase activity was deficient). This cell line can be used as a murine model for Fabry disease studies.

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Genetically Modified Organism (GVO)

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Maria Schröder

Tel. +49 (0) 6221 71415 16

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