Human Tumor Necrosis Factor Receptor Type 1 (TNF-Receptor-1)
| Specifications | |
|---|---|
| Molecular Weight: | 18,3 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 100 ng/mL |
| Activity Assay: | Neutralization of human TNF alpha induced L929 cell cytolysis |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | TNFAR, CD120a, TNFRSF1A, TNFR55 |
| Organism: | Human |
| Accn. No.: | P19438 |
Sequence Information
MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQI EN
Background
Tumor necrosis factor receptor type 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNFa). TNFR1 activates NF-κB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.
- Catalog Number
100-35-5UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
96,00 €
