Human / Mouse / Rat Growth and Differentiation Factor-11 (GDF-11)
| Specifications | |
|---|---|
| Molecular Weight: | 12.5/24.9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 100 ng/mL |
| Activity Assay: | Alkaline phosphatase activity in ATDC5 cells |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
Sequence Information
NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
Background
Growth differentiation factor 11 (GDF-11), also known as bone morphogenic protein 11 (BMP-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.
- Catalog Number
800-04AF-5UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
102,00 €
