Human Interleukin-31 (IL-31)
| Specifications | |
|---|---|
| Molecular Weight: | 15,8 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | Detectable at ≤ 25 ng/mL |
| Activity Assay: | STAT3 Activation in U-87 MG cells |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 20 mM Sodium Phosphate, 50 mM Sodium Chloride, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | None |
| Organism: | Human |
| Accn. No.: | Q6EBC2 |
Sequence Information
SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Background
Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.
- Catalog Number
100-204-500UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
4.428,00 €
