Human Interferon-gamma (IFNg)
| Specifications | |
|---|---|
| Molecular Weight: | 16.9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 0.7 ng/mL |
| Activity Assay: | Activity of HEK-Blue™ IFN-γ Cells |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, 50 mM Sodium Chloride, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | Type II interferon, T cell interferon, Immune Interferon, MAF |
| Organism: | Human |
| Accn. No.: | P01579 |
Sequence Information
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
Background
Interferon gamma (IFNγ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFNγ is produced by T cells and natural killer cells following antigen-specific activation. IFNγ binds IFNγ receptors (IFNγR1 and IFNγR2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFNγ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFNγ is not cross-reactive with mouse IFNγ.
- Catalog Number
100-77-20UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
95,00 €
