Human CXCL11/I-TAC ELISA Kit

Specifications
Reactivity:Human
Specificity:This kit is used for quantitative detection of human CXCL11
Sample Type:Cell culture supernates, serum and plasma(heparin, EDTA).
Sample Size:100 ul
Sensitivity:<10pg/ml
Detection Range:62.5pg/ml-4000pg/ml
Detection Method:Colorimetric
Design Principle:Sandwich
Assay Time:3.5 hours incubations; 1 hour washing and analyzing samples
Additional Information
Target Name:CXCL11
Gene Symbol:CXCL11
Organism:Homo sapiens
Gene ID:6373
Accn. No.:NM_001302123

Background

Chemokine(C-X-C motif) ligand 11(CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant(I-TAC) and Interferon-gamma-inducible protein 9(IP-9). By PCR analysis of somatic cell hybrids, the CXCL11 gene was mapped to chromosome 4, and using FISH, it was located to 4q21.2. The CXCL11 was strongly induced by IFNG and beta-interferon, but only weakly induced by alpha-interferon. Induction of CXCL11 required expression of STAT1. What's more, it found that monocyte chemotaxis occurs in response to recombinant CXCL11. RT-PCR analysis detected CXCL11 expression in brain tissue from a patient with AIDS dementia and a patient with multiple sclerosis but not in 2 controls.
Price
755,00 €
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