Human Bone Morphogenetic Protein-4 (BMP-4)

Specifications
Molecular Weight:13.1/26.2
Tag:None
Source:CHO cells
Purity:≥95%
Activity:15 ng/mL
Activity Assay:Alkaline phosphatase activity induced in ATDC-5 cells
Format:Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Additional Information
Synonyms:BMP-2B
Organism:Human
Accn. No.:P12644

Sequence Information

SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAI VQT LVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR

Background

Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic growth factor family (BMP) and functions as a critical component in the culture and differentiation of stem cells. Active BMP-4 forms a homodimer or a heterodimer with related BMPs, such as BMP-7. BMP-4 is integral for the differentiation of mesoderm and ectoderm from pluripotent stem cells (iPSCs and ESCs) in stem cell cultures. BMP-4 is also used in culturing cardiomyocytes, early hematopoietic cells, hepatocytes, bone, cartilage, adipocytes, and lung cells, as well as inhibiting early neuronal differentiation.
Price
2.371,00 €
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