Biotinylated Cynomolgus IL-2 R beta Protein, His,Avitag™ (MALS verified)
| Specifications | |
|---|---|
| Molecular Weight: | 28.4 kDa |
| Tag: | C-10×His & C-Avi |
| Source: | Biotinylated Cynomolgus IL-2 R beta Protein, His,Avitag (ILA-C82E3) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 (Accession # Q38J85-1). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Organism: | Cynomolgus |
| Accn. No.: | Q38J85-1 |
Sequence Information
Ala 27 - Thr 240
Background
Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit.CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Price
499,00 €
