Animal-free Rat Interleukin-10 (IL-10)

Specifications
Molecular Weight:18.8
Tag:None
Source:E.coli
Purity:≥95%
Activity:Currently undetermined
Activity Assay:Currently undetermined
Format:Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Additional Information
Synonyms:Cytokine synthesis inhibitory factor, CSIF
Organism:Rat
Accn. No.:P29456

Sequence Information

MSKGHSIRGD NNCTHFPVSQ THMLRELRAA FSQVKTFFQK KDQLDNILLT DSLLQDFKGY LGCQALSEMI KFYLVEVMPQ AENHGPEIKE HLNSLGEKLK TLWIQLRRCH RFLPCENKSK AVEQVKNDFN KLQDKGVYKA MNEFDIFINC IEAYVTLKMK N

Background

Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFNƴ), tumor necrosis factor alpha (TNFα), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Mouse IL-10 is not active on human cells.
Price
254,00 €
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