Animal-Free Canine Interleukin-4 (IL-4)
| Specifications | |
|---|---|
| Molecular Weight: | 12,9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 25 ng/mL |
| Activity Assay: | TF-1 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Additional Information | |
|---|---|
| Synonyms: | B-cell stimulatory factor-1, BSF-1, BCDF, BCGF |
| Organism: | Dog |
| Accn. No.: | O77762 |
Sequence Information
MHNFNITIKE IIKMLNILTA RNDSCMELTV KDVFTAPKNT SDKEIFCRAA TVLRQIYTHN CSNRYLRGLY RNLSSMANKT CSMNEIKKST LKDFLERLKV IMQKKYYRH
Background
Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.
- Catalog Number
400-09AF-5UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
106,00 €
