Human Vitronectin / VTN Protein, premium grade
| Specifications | |
|---|---|
| Category: | Other Recombinant Proteins |
| Molecular Weight: | 52.3 kDa |
| Tag: | Native |
| Label / Conjugate: | N/A |
| Source: | Human Vitronectin Protein, Tag Free (VIN-H5214) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Leu 478 (Accession # P04004). |
| Purity: | 95% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Organism: | Human |
| Accn. No.: | P04004 |
Sequence Information
Asp 20 - Leu 478
Background
Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Price
245,00 €
