CPS I Stable Expressing CHO (CHO-CPS45-22) Cell Line

Specifications
Cell Category:Stable Cell Lines
Organism:Hamster
Tissue of Origin:Ovary
Morphology:Epithelial
Culture Properties:Adherent
Marker:CPS I, G418 (500 μg/mL)

Propagation

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Additional Information

Carbamoyl phosphate synthetase I (CPS I), a key enzyme in the urea cycle, was introduced to CHO cells by transfection with calcium phosphate to enable permanent CPS I gene expression. This cell line is suitable for use in the study of the urea cycle. Expression of CPS I results in decreased ammonium ion production, making these cells ideal for research regarding the affect of ammonia levels on cell growth and productivity.

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Maria Schröder

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