Immortalized Human Small Airway Epithelial Cells - SV40

The small airways epithelial cells form a continuous lining to the airways play a unique role as a protective physical and functional barrier to external deleterious agents. These cells function in the regulation of immune responses by contributing to host defense through chemokine production, adhesion molecule expression, and possibly antigen presentation via HLA-DR expression. These cells provide an ideal model for the studies of toxicity, cystic fibrosis, asthma, pathogenesis, pharmacology or airway wound healing.