Immortalized Human Mammary Epithelial Cells (HMEC 2.6)
| Specifications | |
|---|---|
| Cell Category: | Immortalized Cell Lines |
| Organism: | Human |
| Tissue of Origin: | Mammary Tissue |
| Morphology: | Polygonal |
| Culture Properties: | Adherent |
| Immortalization Method: | Serial passaging and transduction with LXSN-based retroviruses carrying hTERT and a mutant CDK4(R24C) |
| Marker: | E-cadherin, EGFR, MIB1, CD10, CK5/14, P63, CK7/18, G418 resistance |
| Donor Gender: | Female |
Propagation
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Additional Information
Immortalized Human Mammary Epithelial Cells (HMEC 2.6) is an immortalized breast epithelial cell line which are not tumorigenic and do not show no anchorage-independent growth. There is a normal distribution of cells in G1, S, and G2/M phase and they express normal breast epithelial markers ( E-cadherin, CK7/18, and CK5/14). The cells retain primary characteristics and are valuable for research relating to mammary epithelial biology.
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Researchers at for-profit organizations and corporations, please contact us for pricing of this item.
Genetically Modified Organism (GVO)
See General Terms.
Product Citations
- Wang, J., & Zhou, Z. (2023) Estrogen-dependent activation of NCOA3 couples with p300 and NF-κB to mediate antiapoptotic genes in ER-positive breast cancer cells Discover Oncology
- Catalog Number
T0454-GVO-ABM - Supplier
ABM - Size
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