Immortalized Human Cardiac Fibroblasts
| Specifications | |
|---|---|
| Cell Category: | Immortalized Cell Lines |
| Organism: | Human |
| Tissue of Origin: | Ventricles (Adult Heart) |
| Morphology: | Multipolar |
| Culture Properties: | Adherent |
| Immortalization Method: | Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen |
Propagation
Please contact us for propagation details.
Additional Information
Human Cardiac Fibroblast is an important heart component that provides structural support for cardiomyoctes. They synthesize extracellular matrix, growth factors and cytokines during growth. In addition, they also interact with myocardial responses to injury and pathophysiological conditions such as scar formation at sites of myocardial infarction, cardiac fibrosis and cardiac hypertrophy. These cells are ideal models for study in cardiac matrix response modeled by physiological and pathological stressors.
Commercial Price Disclaimer
Researchers at for-profit organizations and corporations, please contact us for pricing of this item.
Genetically Modified Organism (GVO)
See General Terms.
Product Citations
- Amrute, J.M., Luo, X., Penna, V. et al. (2024) Targeting immune–fibroblast cell communication in heart failure Nature
- Lavine, K., Amrute, J., Luo, X., Penna, V., Bredemeyer, A., Yamawaki, T., Yang, S., Kadyrov, F., Heo, G., Shi, S., Lee, P., Koenig, A., Kuppe, C., Jones, C., Kopecky, B., Hayat, S., Ma, P., Terada, Y., Fu, A., … Ason, B. (2023) Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis Nature
- Catalog Number
T0446-GVO-ABM - Supplier
ABM - Size
- Shipping
Dry Ice
- Price
- Please inquire
