Immortalized Human Mammary Fibroblasts (HMF3S)
| Specifications | |
|---|---|
| Cell Category: | Immortalized Cell Lines |
| Organism: | Human |
| Tissue of Origin: | Mammary Tissue |
| Morphology: | Spindle shaped |
| Culture Properties: | Adherent |
| Immortalization Method: | Combined transduction with retroviruses carrying a temperature sensitive mutant (U19tsA58) of the SV40 Large T Antigen and a catalytic subunit of human telomerase (hTERT) |
Propagation
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Additional Information
Immortalized Human Mammary Fibroblasts (HMF3S) were generated through the combined transduction of mammary microvascular endothelia cells with a temperature sensitive mutant (U19tsA58) of the SV40 Large T Antigen and a catalytic subunit of human telomerase (hTERT). The HMF3S cells grow best at a temperature of 37⁰C and are not temperature sensitive compared to the Immortalized Human Mammary Fibroblasts (HMF3A) (abm, T0153).
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Genetically Modified Organism (GVO)
See General Terms.
Product Citations
- Hirani, P., McDermott, J., Rajeeve, V., Cutillas, P. R., Jones, J. L., Pennington, D. J., Wight, T. N., Santamaria, S., Alonge, K. M., & Pearce, O. M. T. (2024) Data from Versican Associates with Tumor Immune Phenotype and Limits T-cell Trafficking via Chondroitin Sulfate American Association for Cancer Research
- Catalog Number
T0154-GVO-ABM - Supplier
ABM - Size
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