Biotinylated SARS-CoV-2 Spike NTD (T19R, G142D, EF156-157del, R158G), His,Avitag™
Specifications | |
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Category: | MABSol® Biotin Labeled Proteins |
Molecular Weight: | 36.3 kDa |
Tag: | C-10×His & C-Avi |
Label / Conjugate: | Biotin-labeled |
Source: | Biotinylated SARS-CoV-2 Spike NTD, His,Avitag (SPD-C82H3) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (T19R, G142D, EF156-157del, R158G)). The mutations T19R, G142D, EF156-157del, R158G were identified in the SARS-CoV-2 Delta variant (Pango lineage: B.1.617.2). |
Purity: | 95% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Synonyms: | S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD |
Organism: | SARS-CoV-2 |
Accn. No.: | QHD43416.1 |
Sequence Information
Ser 13 - Leu 303
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Price
416,00 €