SARS-CoV-2 Spike RBD Protein, His Tag (JN.1/Omicron) (MALS verified)
Specifications | |
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Category: | Viral Proteins |
Molecular Weight: | 26.6 kDa |
Tag: | C-10×His |
Label / Conjugate: | N/A |
Source: | SARS-CoV-2 Spike RBD Protein, His Tag (JN.1/Omicron) (SPD-C5249) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,V445H,G446S,N450D,L452W,L455S,N460K,S477N,T478K,N481K,V483del,E484K,F486P,Q498R,N501Y,Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: JN.1/Omicron). |
Purity: | 95% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Organism: | SARS-CoV-2 |
Accn. No.: | QHD43416.1 |
Sequence Information
Arg 319 - Lys 537
Background
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Price
3.493,00 €