Recombinant Human IL17B/IL-17B Protein (Fc Tag)
| Specifications | |
|---|---|
| Molecular Weight: | 45.1 kDa |
| Tag: | C-Fc |
| Source: | Human Cells |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg as determined by the LAL method. |
| Format: | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Additional Information | |
|---|---|
| Synonyms: | IL-17B;IL-20;NIRF;ZCYTO7 |
| Organism: | Human |
| Accn. No.: | Q9UHF5 |
Sequence Information
Gln21-Phe180
Background
Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.
Price
125,00 €
