Recombinant Human FGF-7/KGF Protein (Active)
| Specifications | |
|---|---|
| Molecular Weight: | 19.1 kDa |
| Source: | E.coli |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per µg as determined by the LAL method. |
| Activity: | Immobilized Human KGF at 2μg/ml(100 μl/well) can bind Human FGF R3-Fc(Cat: PKSH033678). The ED50 of Human KGF is 0.788 ug/ml . |
| Format: | Lyophilized from a 0.2 μm filtered solution of 20mM PB,pH8.0,l50mM NaCl. |
| Additional Information | |
|---|---|
| Synonyms: | Fibroblast growth factor 7;FGF-7;Heparin-binding growth factor 7;HBGF-7;Keratinocyte growth factor;FGF7;KGF |
| Organism: | Human |
| Accn. No.: | P21781 |
Sequence Information
Cys32-Thr194
Background
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor; whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Price
322,00 €
