Insulin Receptor Pathway Phospho Antibody Array (219 antibodies, six replicates of each)
| Specifications | |
|---|---|
| Product Category: | Phosphorylation Profiling |
| Semi- / Quantitative: | Qualitative/semi-quantitative |
| Solid Support: | Glass Slide |
| Design Principle: | direct labeling |
| Detection Method: | Fluorescence |
| Organism: | Human, Mouse, Rat |
| Number of targets: | 219 antibodies; 6 replicates per antibody |
| Internal Controls: | beta-actin; GAPDH; Negative controls |
Insulin Receptor Phospho Antibody Array features 219 highly specific antibodies related to insulin receptors. The array is designed for protein phosphorylation profiling in cell and tissue samples from human, mouse, and rat. Each package contains two identical array slides for analyzing two samples, such as a control sample and a treatment sample.
Compatible Sample Types
cell lysates; frozen or FFPE tissue lysates
Target Names
4E-BP1 (Ser65), 4E-BP1 (Thr36), 4E-BP1 (Thr45), 4E-BP1 (Thr70), AKT (Ser473), AKT (Thr308), AKT (Tyr326), AKT1 (Ser124), AKT1 (Ser246), AKT1 (Thr450), AKT1 (Thr72), AKT1 (Tyr474), AKT1S1 (Thr246), AKT2 (Ser474), AMPK1 (Thr174), AMPK1/AMPK2 (Ser485/491), AMPKbeta1 (Ser182), ATP-Citrate Lyase (Ser454), BAD (Ser112), BAD (Ser134), BAD (Ser136), BAD (S...
Product Description
The ELISA based Antibody Array platform involves four major steps: 1) Protein extraction with non-denaturing lysis buffer; 2) Biotinylation of protein samples; 3) Incubation of labeled samples with antibody array; and 4) Detection by dye conjugated streptavidin.
Other Materials Required
Antibody Array Assay Kit for easy and reliable processing of antibody arrays. Mandatory for all Full Moon Biosystems Antibody Arrays.
Array Scanning Service Free of Charge
In case you do not have access to a compatible laser scanner a scanning service for all Full Moon BioSystems antibody arrays can be offered for free. Only shipping charges apply. Please contact us by email, phone or using this form for further details.
Product Citations
- Rebollo‐Hernanz M, Zhang Q (2019) Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation Between Macrophages and Adipocytes in vitro Mol Nutr Food Res. 2019 Apr 24:e1801413
- Fischer HJ, Sie C (2017) The Insulin Receptor Plays a Critical Role in T Cell Function and Adaptive Immunity J Immunol. 2017 Mar 1;198(5):1910-1920
- Luna-Vital D, Weiss M (2017) Anthocyanins from Purple Corn Ameliorated TNF-α-Induced Inflammation and Insulin Resistance in 3T3-L1 Adipocytes via Activation of Insulin Signaling and Enhanced GLUT4 Translocation Mol Nutr Food Res. 2017 July 31, doi: 10.1002/mnfr.201700362
- Rozenberg K, Smirin P (2014) Insulin-sensitizing and insulin-mimetic activities of Sarcopoterium spinosum extract Journal of Ethnopharmacology, August 8 2014, 155(1): 362-372
- He H, Zong Y (2009) Sensing the Insulin Signaling Pathway with an Antibody Array Proteomics Clinical Applications 2009;3:1440–1450
- Catalog Number
PIG219-FM - Supplier
Full Moon BioSystems - Size
- Shipping
Blue Ice
Price
957,00 €
