Recombinant Human ADAM8/CD156a protein (His tag)

Specifications
Molecular Weight:71.7 kDa
Tag:C-His
Source:HEK293 Cells
Purity:> 95% as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU/mg of the protein as determined by the LAL method.
Format:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Additional Information
Synonyms:ADAM 8;CD antigen CD156a;Cell surface antigen MS2;Disintegrin and metalloproteinase domain-containing protein 8;EC 3.4.24.;MS2
Organism:Human
Accn. No.:P78325

Sequence Information

Met1-Ser653

Background

ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. It can be activated and assayed under the conditions described in the Activity Assay Protocol.
Price
1.454,00 €
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