Recombinant Mouse TNF-α protein (His tag)

Specifications
Molecular Weight:17.1 kDa
Tag:N-His
Source:E.coli
Purity:> 95% as determined by reducing SDS-PAGE.
Endotoxin Level:< 10 EU/mg of the protein as determined by the LAL method.
Format:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Additional Information
Synonyms:Cachectin;DIF;Membrane Form;TNF-Alpha;TNF-a;TNF-alpha;TNFSF2;TNFalpha;Tnf;Tnfa;Tnfsf1a;Tnfsf2;Tumor Necrosis Factor;Tumor Necrosis Factor Ligand Superfamily Member 2
Organism:Mouse
Accn. No.:P06804

Sequence Information

Leu 80–Leu 235

Background

Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.
Price
518,00 €
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