Recombinant Mouse IL7 Protein(Sumo Tag)

Specifications
Molecular Weight:27 kDa
Tag:N-Sumo
Source:E.coli
Purity:> 90 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method
Format:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Additional Information
Synonyms:IL 7;IL-7;Il7;IL7;Interleukin 7;Interleukin-7;LP-1;Lymphopoietin 1
Organism:Mouse
Accn. No.:P10168

Sequence Information

Glu26-Ile154

Background

IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCR?) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.
Price
518,00 €
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